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Use of the zoneX #6 20 mg pouch resulted in significantly higher levels of blood plasma nicotine (assessed using comparison of C max , AUC t and AUC 0-inf (detailed in Table 2)) compared to the other three study products, which did not demonstrate significantly different blood plasma nicotine profiles to one another

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The timeframe is normally less than six months

Studies tracking former tobacco users over time showed that roughly ten years after quitting, periodontal disease risk falls close to the level of someone who never smoked

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